folic acid antagonists การใช้

• It may be prescribed in the treatment of toxoplasmosis retinitis, in combination with the folic acid antagonists pyrimethamine and sulfadiazine.
• The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs.
• Folic acid, for example, can interfere with the action of some chemotherapeutic drugs, like methotrexate, that act as folic acid antagonists.
• That same year, Milunsky, Graef, and Gaynor reported cases of cleft lip and palate associated with attempted abortion with methotrexate and aminopterin, which are folic acid antagonists.
• He focused his time on cancer research, and was " the first to define the significance of folic acid in the biology of cancer " and was " among the first to use folic acid antagonists clinically ".
• The dictionary definition should be enough to scare arthritis out of anyone's body _ " an orange-brown, crystalline powder, C20H22N8O5, that is a folic acid antagonist : used in medicine, especially in treating leukemia and various tumors ."
• Dr . Sidney Farber received the Lasker in 1966 for his 1947 discovery that a combination of aminopterin and methotrexate, both folic acid antagonists, could produce remission in patients with acute leukemia, and for " his constant leadership in the search for chemical agents against cancer ".